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Clinically relevant categories were used for UACR because a high proportion of the skewed data were truncated to zero, making transformation difficult, and the predictive performance of the models was better using these categories than when using log-transformation.
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This is probably because the remaining abdominal segments look very similar, making homeotic transformations difficult to identify.
This transformation is difficult to initiate and is severely retarded by the presence of alloying elements or trace impurities.
Due to these characteristics, the hypothesis of malignant transformation was difficult to asses.
The analyticity and regularity of transformation are difficult to be proved in the space (l^{a,s}).
Since the impulse response of linear transformation is difficult to compute without prior knowledge, we propose a simpler and more accurate approximation algorithm.
The fact that Groupon has been doing this in the midst of being a publicly traded business, and all of the demands of reporting as a result of that, has made the transformation especially difficult at times.
Transformation is difficult because understanding often comes at the cost of your ego.
This transformation is difficult to achieve chemically due to inertness of C H bonds of saturated hydrocarbons.
In soybean, Medicago truncatula and other plants for which stable transformation is difficult, transgenic "hairy roots" generated through A. rhizogenes-mediated transformation are often used to investigate gene function.
Compared with other plants with smaller genomes, the use of most genetic and molecular techniques to study genes involved in wheat– Pst or wheat– Bgt interactions has been limited, because hexaploid wheat has a large and complex genome and its transformation is difficult, and both fungi show sexual reproduction and irreversible deletion of genes dispensable for biotrophy [ 10, 12].
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