Sentence examples for transformation demonstrating that from inspiring English sources
Our results show that BRAF, KRAS and PIK3CA mutations occur prior to malignant transformation demonstrating that these oncogenic alterations are primary genetic events in colorectal carcinogenesis.
Results of the model have been confirmed by isogenic transformation demonstrating, that an A501V(T) mutation in PBP2 results in increased MIC to ceftriaxone in a non-mosaic penA containing strain [ 82].
Moreover, single amino acid substitutions within the ComFA nucleotide triphosphate hydrolase (NTPase -active site pheNTPase -activeomFA deletion in itsitefect on genetic transformation, demonstrating that the NTphenocopiedtheis comFAal to ComFA function [ 8].
Additionally, germline transformation demonstrated that a 9.4 kb genomic DNA segment containing the alpha-amanitin-resistant allele, RpII215C4, includes all sequences required to produce amanitin-resistant transformants.
Although it is only a small gesture I think for someone with a perspective as staunch as his to experience transformation demonstrates that the equality movement is truly moving forward.
This transformation demonstrated that the effect of DFMO was even greater than initially perceived.
These transformations demonstrate that the R residue serves as a diastereocontrol element for building various chiral ortho-aliphatic α-branched phenols and the subsequent reactions within the benzopyran ring.
This led to the abrogation of TRK-T3 induced differentiation and transformation, thus demonstrating that signalling through tyrosine 291 is essential for oncogene activity and it cannot be compensated by possible TRK oncogene-specific signal transduction pathways.
To our knowledge, these studies are the first to implicate P311 in myofibroblast transformation, to demonstrate that transformation may occur independently of TGF-beta1, and to suggest that P311 may prevent fibrosis.
Expression of function-blocking Notch ligands abrogated HMEC transformation by Wnt1, demonstrating that there is a need for Notch signalling.
We show these results as they justify our transformation approach by demonstrating that it preserves essential properties of the Boolean model.
