While there were 31 transfers observed in the study population, none were timely transfers which could explain the cases of ART attrition we observed.
In the case of the fluoroarenes a competitive hydride transfer pathway could explain the hydrodefluorination products.
198 Apparently, lack of the GPI anchor on PrP would prevent its transfer and could explain why cells expressing GPI anchor-less PrP were unable to sustain a scrapie infection over time.
The immaturity of the neonatal immune system and the impact of passively transferred maternal antibodies could explain the poor immune response in infants vaccinated at birth [ 43].
This potential of transfer via bacteriophage could explain our results and, notably, the presence of the sea gene in MSSA strains.
A high frequency of transfer in vivo could explain the diversity of MGEs described in comparative population genomic studies of a wide variety of S. aureus, even between isolates belonging to the same lineage (Holden et al. 2004, 2013; Lindsay et al. 2006; Harris et al. 2010; McAdam et al. 2012; McCarthy, van Wamel, et al. 2012).
Similarly to the above mentioned URA1, this may also represent a case of horizontal gene transfer [ 72], which could explain its absence from A. gossypii.
370 In addition, EMV-mediated transfer of genetic information could explain the observed plasticity and the functional effects of stem cells without the need for their transdifferentiation into tissue cells.
Therefore, if the spread of huα-syn we observe is due to an axonal transport from the OB to interconnected region, transport along axons in both directions, combined with cell-to-cell transfer at synaptic sites, could explain why we observed huα-syn in brain regions outside the OB.
The active chromosomal reorganization of numerous genes acquired by horizontal transfer, mainly from mobile elements, could explain this phenomenon.
