Sentence examples for transferred t from inspiring English sources

Yee, C. et al. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells.

Wall, E. M. et al. Spontaneous mammary tumors differ widely in their inherent sensitivity to adoptively transferred T cells.

Hegde, M. et al. Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.

An ideal safety switch should be capable of depleting the transferred T cells with minimal injury to normal tissues.

The costimulatory properties of second-generation chimeric antigen receptors (CARs) determine the overall potency of adoptively transferred T cells.

A possible explanation for the uneven efficacy of these treatments is the inability of the transferred T cells to accomplish tumor killing.

In immuno-compromised mice, CH12-MMAF eliminated the majority of transferred T cells expressing FR806 and anti-CD19 chimeric antigen receptor (CAR).

Here, we present an overview of gene-engineering approaches and considerations to improve tumor-selectivity and effectiveness of adoptively transferred T cells.

By engaging programmed death 1 (PD-1) on activated T cells, PD-L1+ tumors directly render tumor-specific T cells, including adoptively transferred T cells, functionally exhausted.

Recent reports on the impressive efficacy of adoptively transferred T cells to challenge cancer in early phase clinical trials have significantly raised the profile of T cell therapy.

A mismatch between the chemokines released by the tumor or tumor stroma and the chemokine receptors expressed on the transferred T cells may also impede T cell homing.