To examine the transferability of single-ancestry GWASs, we used published summary statistics to calculate polygenic risk scores for eight well-studied phenotypes.
The transferability of the results from this single case study is in turn supported by: (a) the in-depth description of our case which helps the reader to better appreciate the influence of the case's context; and (b) the critical nature of the case in question, a particularly complex FMG whose structure and organizational dynamics were very different from more typical FMGs.
As this was a study in a single institution, the transferability of the results may be limited, although we purposively sampled participants to represent different professional backgrounds, gender, and assessment experience, and all participants had assessment experience in two or more different medical programs.
For most organisms indeed, whole genome surveys are often hampered by a shortage of genomic sequences and/or a lack of interspecific transferability of known molecular markers such as microsatellites or single nucleotide polymorphisms (SNPs) [ 3, 4].
Since the study as performed at one ED (single center design) the question of transferability of the results remains unanswered.
Both question three and four pertain directly to the issues related to Acceptability and Transferability of the interactions suggested in the responses to the single-item Likert questions.
A purposive sample of informants from one profession, all interviewed by a single investigator, poses potential threats to credibility and transferability of findings.
A weakness of using a single-case study design is the limited transferability of the results.
We review the transferability of obesity-susceptibility loci (identified by genome-wide association studies) using both single nucleotide polymorphism (SNP) and locus-wide comparisons.
In terms of epidemiology, the specific effects of the single pollutants on health are not considered thus the transferability of the results of the present study to contexts other than the Campania region is limited.
The present study addresses the transferability of disease associations across human populations by examining levels of population differentiation at disease-associated single nucleotide polymorphisms (SNPs).
