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Table 1 provides a checklist of factors that influence the applicability or transferability of guidelines.
The checklist does not include any specific recommendations related to supporting judgements about the applicability or transferability of guidelines, or their local adaptation.
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We reviewed the literature on applicability, transferability, and adaptation of guidelines.
Although the adjustment method presented in this paper is not sufficient to suggest that utilities should be considered transferable in pharmaco-economic guidelines, it can increase the transferability of utilities regardless of the local guideline's standpoint.
34 In determining whether those results can be generalized to other settings, such as Canada, one must consider the International Society for Pharmacoeconomics and Outcomes Research guidelines on the transferability of health economic models across jurisdictions.
11 It appears that more recent versions of guidelines pay an increasing attention to the issues with the transferability of utilities and are more restrictive in their acceptance of data from other countries.
The variation in methodological quality of the economic evaluations in newborn screening which is detected through application of the guidelines, and which limits the comparability, generalizability and transferability of economic evaluation results, reveals the necessity for specific guidelines regarding the methods for conducting sound economic evaluations in newborn screening.
It would be useful to further understand more about the transferability of the TDFI approach by assessing whether those tasked with eliciting behaviour change to improve the uptake of guidelines in healthcare organisations are able to apply the model in practice.
Guidelines, there are multiples forms of guidelines.
The combination of participants in the study, together with the fact that the local guidelines were very similar to the national guidelines and also to the European guidelines, could be considered a ground for transferability of the results, as these local experiences might be assumed to be universal and to reflect those of GPs in other parts of the country, and probably also in other countries.
International pharmaco-economic guidelines take different standpoints on the transferability of utility values.
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