In recent years, NIS gene transfer therapy to confer non-thyroid cancers the sensitivity to radioiodide ablation therapy has been widely investigated as a potential therapeutic strategy for human cancers [18], [42], [43].
Thus, it may be necessary for a transferred gene to confer a benefit to its new host in order to be stably maintained in the host genome over the long term.
The N-terminal RxLR-dEER double-motif in haustoria forming Oomycete plant pathogens has been documented to confer transfer across the EHM [ 5, 6], a function required by some haustoria secreted effectors.
Horizontally transferred genes are thought to confer biological properties, which are beneficial to the host organism.
Research investigating fern genomics and proteomics could yield new tools for molecular biology including promoters and genes responsible for arsenic accumulation pathways that can be transferred to other organisms to confer value-added traits for academic research and industrial applications.
Serum transfer from vaccinated animals is sufficient to confer protection from influenza-associated illness in naïve mice.
Moreover, T cells isolated from the non-draining lymph nodes nLN, cLN and the spleens of FTY720-treated BALB/c, Cd81−/− or Cd81+/+ mice immunized s.c. with γ-spz were incapable to confer protection by adoptive transfer.
Non-conventional methods have also been used successfully to confer virus resistance by transferring primarily virus-derived genes, including viral coat protein, replicase, movement protein, defective interfering RNA, non-coding RNA sequences, and protease, into susceptible plants.
In addition, the N-terminal 24 amino acids and the C-terminal 49 amino acids of FGF19 are necessary for full FGFR4 activity, but are not sufficient to confer FGFR4 activity when transferred to FGF21.
Maternal immunoglobulins are transferred from the mother to the offspring in order to confer passive immunity during early life.
