However, it is unclear if and how well such classifiers would transfer to proteins of unknown function.
By avoiding the transfer of foreign or unknown DNA, crops developed through intragenesis or cisgenesis mimic the conventionally bred cultivars.
The direction of this route of transfer is unknown, as are the potential health risks arising from this transfer.
In this paper we are not interested in optimizing a method of predicting protein functions, but rather in evaluating an aspect of function prediction that has been somewhat neglected previously, namely whether classifiers trained on proteins of known functions can be expected to transfer successfully to proteins of unknown function.
In this paper, an inverse problem of heat transfer in the glass forming process is studied to determine a number of unknown heat transfer coefficients.
It remains to be seen how well transfer of genetic information to unknown recipients in natural biofilms or sludge flocs can be quantified.
It was analyses of the yeast VMA inteins, all of which contain a LAGLIDADG HEG, which suggested the possibility of frequent horizontal transfer between species of ascomycete yeasts although the mechanism for such a transfer of nuclear genes is unknown [ 17, 18].
Finally, emergency departments at larger hospitals had more patients transferring in, so some patients with fever of unknown origin may have been transferred from lower level hospitals.
The detailed mechanism of ammonia transfer is unknown, but likely involves a conformational rearrangement in the vicinity of a putative channel that connects the two domains (Endrizzi et al., 2004; Goto et al., 2004).
One possible explanation is that, in more recent years, the aetiology of severe ID is being increasingly identified through new genetic techniques, 25 26 and thus there has been a diagnostic transfer from those with severe ID of unknown cause to those with a biomedical cause over time.
