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Because atherogenesis is dependent on the transendothelial transfer of monocytes into the intima, it is not surprising that deletion of the MCP-1 gene leads to a reduction in atherogenesis in experimental models of atherosclerosis (17).
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Adoptive transfer of IMs to monocyte-depleted CCR2-DTR recipient mice rescued priming of C7 T cells.
Phase I clinical trials involving the autologous transfer of αGC-pulsed monocyte-derived dendritic cells (moDC) were conducted in patients with different types of cancer [ 4, 11, 13– 16].
In this review we discuss recent findings that have started to unravel the complexity of migratory intestinal cDCs, including assessment of the precursor-product relationships of transferred monocytes and cDC precursors, the identification of novel markers that appear to distinguish cDCs and monocyte-derived MΦs and new models that shed light on their in vivo functionality.
NBL cells secrete miR-21-5p in EVs transferred to monocytes, activating the NF-κB pathway and upregulating miR-155-5p miR-155-5p miR-155-5p
So is also the transfer of seeding activity from monocytes isolated from group H2 mice.
This transfer of seeding activity with monocytes isolated from mice in the H groups to mice in the J groups did not involve any AEF injection.
10.7554/eLife.01086.006 Figure 3. Adoptive transfer of highly purified inflammatory monocytes can rescue antigen transport and CD4 T cell priming in DT treated CCR2-DTR mice.
As pointed out, the mechanism of antigen transfer between monocytes and resident DCs remains unclear.
This rapid accumulation of transferred monocytes within the lymphoid tissues, particularly in IM7-treated mice, provides an explanation for the sudden loss of circulating fluorescent cells in the retina observed by SLO.
Activation of monocytes by Th1 cell transfer may have a role in improved CST sprouting and myelination after SCI, as monocyte-derived cells are required for remyelination after toxin-induced demyelination or EAE.
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