Sentence examples for transfer of histone from inspiring English sources

In order to investigate the mechanism of transcriptional reprogramming by oocytes, we have first monitored the transfer of histone variants between the oocyte and the transplanted nuclei.

This report also provided evidence that histone modifications are lost from parental histones during passage of the replication fork, making the transfer of histone modifiers to the daughter strands the prime mechanism for conservation of histone modification through S-phase.

In turn, it has also been suggested that incomplete transfer of histone modifications may inhibit cell cycle progression through G1, so preventing consistent erosion of histone modifications during S-phase [ 52].

Nucleoplasmin is a nuclear chaperone protein that has been shown to participate in the remodeling of sperm chromatin immediately after fertilization by displacing highly specialized sperm nuclear basic proteins (SNBPs), such as protamine (P type) and protamine-like (PL type) proteins, from the sperm chromatin and by the transfer of histone H2A-H2B.

This might suggest that Chd1 is recruited to the gene body via the elongation complex and is then targeted to the nucleosome substrate via binding to the exposed DNA loop immediately adjacent to the histone octamer to facilitate the in cis transfer of histone octamers.

Single-molecule optical trap experiments suggest that PolII transcribes through a nucleosome by the in cis transfer of histones, particularly the H3 H4 tetramer, to DNA upstream of PolII via the formation of a transient DNA loop (Hodges et al., 2009; Kulaeva et al., 2009; Bintu et al., 2011).

We provide the first conclusive evidence of a horizontal gene transfer of a Histone H4 Lysine 20 (H4K20) modifier, Set8, from an animal host to the ancestor of apicomplexans.

The transfer and deposition of histone variants into chromatin is mediated via their association with specific histone chaperones.

Finally, when the rates of transcription are even higher, enough DNA is unwrapped from the surface of the histone core that the complete histone detachment from DNA greatly outcompetes the rates of histone transfer and histone histone dissociation, thus leading to bare DNA formation.

Previous works have shown that SET7/9 exhibits broad substrate specificity catalyzing methyl transfer to a variety of histone and non-histone proteins including H3, TAF10, TAT, RelA, p53 and FoxO3 [ 5, 32].

To understand the mechanism of histone H3/H4 transfer among Asf1, CAF-1, and DNA from a thermodynamic perspective, we measured the binding affinities for their various complexes.