Sentence examples for transfer of cholesterol from inspiring English sources
The design was guided by computational modeling based upon a model for the transfer of cholesterol between two proteins, NPC1 and NPC2.
Two modified cholesterol residues were covalently joined by a tether based on molecular modeling of the transient interaction of NPC1 and NPC2 during the transfer of cholesterol from the binding site of one of these proteins to the other.
We demonstrate herein a newly developed serum total cholesterol biosensor by using the direct electron transfer of cholesterol oxidase (ChOx), which is based on the immobilization of cholesterol oxidase and cholesterol esterase (ChEt) on potassium-doped multi-walled carbon nanotubes (KMWNTs) modified electrodes.
By itself, this discovery did not identify the mechanism by which the ABCA1 protein facilitates transfer of cholesterol to HDL, but good evidence suggests that it acts upstream of actual transfer of cholesterol from the cell.
The rate-limiting step in ACTH-stimulated cortisol synthesis, the transfer of cholesterol from the outer to the inner mitochondrial membrane, is mediated by StAR [7], [10], [37].
Little is known about the protein(s) involved in the intracellular transfer of cholesterol in insects.
To further study nature of the cholesterol gradient in pRBC, we probed for signals of Di-4 fluorescence that might provide evidence for transfer of cholesterol-rich complexes between the pEM and PVM.
In transgenic mice (that normally lack CETP) with CETP gene transfer, the transport of cholesterol from macrophages to the liver was increased (Tanigawa et al, 2007).
Tanigawa et al. found that hepatic CETP gene transfer in mice stimulated the transport of cholesterol from peritoneal macrophages to the liver, followed by its elimination as bile acids.
Since HDL is the main cholesterol esterification site in the plasma compartment, decrease in the transfer of unesterified cholesterol to this lipoprotein fraction can interfere with the esterification process, which is critical for the stabilization of the plasma cholesterol pool and the reverse cholesterol transport.
In those patients, among other changes in lipid transfers, the transfer of unesterified cholesterol to the HDL fraction was diminished, independent of the HDL-cholesterol levels [ 18].
