Your English writing platform
Discover LudwigExact(23)
The most common approach in computational prediction of protein function is to use sequence or structure similarity to transfer functional information between proteins [2].
Insights of ecological dynamics suggest that donor sports and team sports share adjacent areas or fields of an affordance landscape [17] that include an extensive range of opportunities for action which can transfer functional performance behaviours from a donor sport to a target sport [9].
Immature DCs secrete exosomes and can transfer functional MHC-peptide complexes to activated DCs.
This study aimed to transfer functional annotations between protein structures based on the local structural and evolutionary similarities of their functional sites.
We demonstrated that Dex could transfer functional MHC class I and class II/peptide complexes to DCs leading to the priming of CD8+ and CD4+ T cells respectively [39] [41].
Hence, outparalogs cannot be used to transfer functional assignments between species.
Similar(37)
We formed broad classes of functionally related OGs by transferring functional annotations from homologs based on the COG functional classification schema (Tatusov et al. 1997) and from predictions, for example, signal peptides or host cell translocation motifs (RXLR and LXLFLAK) (supplementary additional file 2, Supplementary Material online).
Similarly wired proteins in the protein protein interaction networks (PINs) are shown to carry out similar functions and that fact has been exploited for transferring functional annotations between proteins (Milenković and Pržulj, 2008; Nabieva et al., 2005; Samanta and Liang, 2003; Vazquez et al., 2003).
Typically, a small tag peptide sequence incorporated into the target protein is recognized by the post-translational modification enzyme as a substrate and then transfers functional moieties from an analog of its natural substrate onto the tag (Fig. 23).
Protein families, in turn, have proven to be invaluable in studying evolution and for inferring and transferring functional annotation across species.
Functional annotation is normally done by transferring functional information across organisms using comparative analysis.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com