Wakayama, S. et al. Propagation of an infertile hermaphrodite mouse lacking germ cells by using nuclear transfer and embryonic stem cell technology.
Furthermore, novel therapies in the current decade, such as molecular-targeted, gene transfer, and pluripotent stem cells therapies, have led to numerous emerging ethical challenges or different ethical assessment and justification frameworks for FIH research.
Light-induced dielectrophoresis provides a non-invasive, quantitative, and reproducible means to select embryos for applications including IVF transfer and embryonic stem cell harvest.
The focus on novel technologies that are vital for innovative in vivo research has been expanded to include chapters on the use of transgenic and gene transfer technologies, nanotechnology, and stem cells.
Despite having genetic causes, strategies (such as gene transfer, protein delivery and stem cell transplantation) that can shift this equilibrium towards muscle regeneration can offer time and hope for patients suffering from these debilitating conditions.
2, 8, 9 A variety of types of cancer immunotherapy, such as epidermal growth factor receptor (EGFR) signaling inhibitors, cetuximab, dendritic cell (DC) vaccines, adoptive CTL transfer and allogeneic hematopoietic stem cell transplantation with donor lymphocyte infusion, have been performed in pilot studies for head and neck patients.
Promising research has been conducted in recent years that have the potential to affect the development of new treatment approaches for salivary gland dysfunction including growth factors, gene transfer, artificial salivary glands, and stem cell transplantation (reviewed in [ 17]).
In addition, experimental animal studies and clinical trials suggest that the transfer of stem and progenitor cells into the myocardium has a favorable impact on tissue perfusion and contractile performance [11], which have been corroborated with neovascularization and myocyte formation [12], [13], [14].
Walker at al. [ 25] discovered fundamental changes in the load transfer between stem and bone when comparing contact pressures between femoral bone and standard length straight stems or stems with a lateral flare.
The inability of recombinant retrovirus to transduce non-dividing cells prompted several studies to determine optimal cocktails of growth factors and/or extracellular matrix molecules to promote gene transfer to slowly diving cells and stem cells.
