Sentence examples for transducer channel from inspiring English sources

A putative geometrical model of the transducer channel pore is presented that draws on results from all the three classes of permeant blockers.

This chapter presents recent experiments designed to infer the properties of the ion-conducting pore of the mechanoelectrical transducer channel of sensory hair cells using permeant blockers.

By combining results from experiments with three classes of large cationic permeant blockers, the fluorescent dye FM1-43, the aminoglycoside antibiotics, and the potassium-sparing diuretic amiloride, information has been obtained on the free energy profile along the transducer channel's pore as sensed by these blocker molecules.

Even when strong transducer channel candidates have been identified, as in nematode touch cells and insect bristles, the mechanism by which these channels open is still unclear.

Such variability may reflect differences between OHCs in the numbers of intact tip-link – transducer channel complexes surviving experimental procedures, a variable that may also differ between the strains of mice used.

The data support a role for NOMPC as a primary transducer channel, because it is located at sites where mechanical signals impinge on the sensory cilia in both external and chordotonal organs.

An unacceptably large amount of transducer channels (more than 4000) must be used, if the conventional phased array transducers are extrapolated to the 2D case.

For the +/v2J OHCs this shift resulted in an increased fraction of the transducer channels open at rest.

For more positive membrane potentials, fluid jet stimuli in the positive direction caused outward currents and the fraction of transducer channels open without stimulation increased, probably as a consequence of reduced adaptation due to a decreased driving force for Ca2+ ions through the transducer channels [32].

The hair cells load with FM1-43, a dye that is known to enter hair cells via their transducer channels [26], and they are sensitive to aminoglycoside antibiotics, compounds also known to be permeant blockers of the hair cell's transducer channels [30].

Determining the location of candidate transducer channels within or relative to these structures can help to confirm the function of the channels and to understand how they are activated.