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The sRNAs incorporate into specific AGO-associated RNA-induced silencing complexes (RISCs), and guide the complexes to the target transcripts to perform cleavages.

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Further 5' and 3'RACE analyses will be necessary to obtain full-length transcripts and to perform other sequence comparisons and functional analysis.

We used our model cell transcript distributions to perform Monte Carlo simulations of microarray experiments comparing samples from two halves of the same cell and from pairs of identical cells.

Identified transcripts were used to perform hierarchical clustering analysis of 72 microarray experiments performed on fibroblasts derived from normal males, and individuals affected with PAIS and CAIS.

There remain several areas requiring standardization, e.g., a defined, consensus set of gene transcripts against which to perform clinical annotation must be decided.

Considering ESTs TTC05519 and TTC05755 sequence similarities with Tctex1 and their differential testis expression in T. thynnus, we propose these transcripts are likely to perform a similar function to that of TCTEX1 and as such are a notable aspect of the differentiation between the testis and ovarian transcriptomes of T. thynnus.

Dali is unusual in acting in a transcript-dependent manner to perform both local and distal gene regulatory roles like another such lncRNA, Paupar (Vance et al., 2014).

Likely explanations include poor quality of the transcript libraries used to perform the inference, sequencing library preparation biases not corrected for by the algorithms, and possible inaccuracies in qPCR estimates.

For a more refined control of novel isoforms, or for organisms with poor transcript annotations, users are suggested to perform novel transcript assembly using tools like Cufflinks [22] and then load the resulting gene and transcript annotations (GTF) into PrimerSeq.

The number of DE antisense transcripts was too small to perform a GO enrichment analysis.

However, the lack of functional information for a large fraction of the differentially regulated transcripts limited our ability to perform a more comprehensive bioinformatics analysis of the biochemical and signaling pathways differentially regulated during senescence.

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