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For example, IκBζ provides transcription ability to p50 homodimers when complexed with them.
To explore whether this pattern exists in the zebrafish genome, we used ESTs to represent the transcription ability of these retrogenes, because they provide better discrimination within close paralogs than short-tag expression sequences or data from hybridization-based methods [ 36, 37].
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As described in the previous study [ 18], 23 promoter candidates were selected from Vibrio parahaemolyticus, Vibrio cholerae, E. coli and Vibrio anguillarum, and their transcription abilities were investigated with pUTtG as screening vector and iron chelator 2,2'-dipyridyl as inducer.
Therapeutic-antagonists of oestrogens will be re-designed and biosynthesised and deployed to circumvent the gene DNA-transcription abilities of oestrogens and mimics: and their metabolites in oestrogen-target tissues (see above).
These results support the notion that stabilization of BMAL1 protein levels might lead to reduction in its transcription activation ability [28].
E2F1 executes most of its biological functions through its transcription activator ability.
We hypothesize that Sox2 in RU and RR cells are biochemically distinct, allowing for differential transcription activation ability at unique promoter regions.
Unlike class A Hsfs, most of the class B and C Hsfs do not have the transcription activation ability, since their CTDs lack detectable the AHA motifs.
While this argues for an important role of the cellular context in modifying transcription factors' ability to control cell fate, the extent to which the cellular environment affects the function of transcription factors is unclear (Pan et al, 2009).
In addition to receiving the phosphosignal at Asp54 from DevS and DosT kinases [16], [17], [23], DevRN suppresses the DNA binding and transcription-activating ability of unphosphorylated DevR under aerobic conditions, sponsors cooperative binding of DevR with secondary binding sites, and it is required for sustaining DevR stability and autoregulation during hypoxia.
A key advantage of RNA-Seq over previous microarray-based methods for assessing transcription is the ability to query all transcripts on a genome-wide scale without prior knowledge about the locations and structures of genes.
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