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Sentence examples for transcriptase from inspiring English sources

Dictionary

transcriptase

noun

A polymerase that catalyzes the transcription of DNA to RNA.

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Exact(53)

As in the embryo experiments, he then silenced the cancer-cell genes that produced reverse transcriptase, and likewise found the tumours grew more slowly.

Reverse transcriptase makes part of the cell's protein publishing line work backwards, recreating DNA, a molecule in which organisms typically store genetic information, from its less stable and correspondingly less favoured cousin, RNA.

Seven of the ten genes Dr Spadafora tested were active in healthy embryos, but were shut down in the nevirapine-arrested ones.Since cancer cells also contain a lot of reverse transcriptase, Dr Spadafora wondered whether stopping the enzyme working might stop them dividing as well.

One works by inhibiting the activity of a viral enzyme called reverse transcriptase.

And in Dr Spadafora's mouse experiments, reverse transcriptase in sperm has very occasionally turned foreign RNA into DNA, which has then found a place in the nuclear genome.Although unlikely to have any effect if it did happen, the principle is cause for concern.

Curiously, as a result of the reprogramming, both contain appreciable amounts of an enzyme called reverse transcriptase that biologists more usually associate with certain viral infections, including HIV.

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Similar(7)

Second, he checked the drug was not bad for the embryos in some other, unknown, way by specifically turning off reverse transcriptase-producing genes.

Its stable of AIDS drugs will be joined next year by two promising new compounds, a protease inhibitor called 141W94 and a reverse-transcriptase inhibitor called 1592.

The American firm has developed a drug called Sustiva, part of a new family of compounds known as non-nucleoside reverse-transcriptase inhibitors.

Instead, they are combined with a second class of drug, known as reverse-transcriptase inhibitors, that block the copying of viral genes into a form which can enter a host cell's nucleus (a process known as reverse transcription).

There are thousands of reverse-transcriptase genes in the genomes of all mammals.

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