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Other studies show that the increased level of active Nrf2 is directly related to the IRES sequence (internal ribosome entry sequence) contained in the Nrf2 transcript, which is responsible for transcription-dependent redox state [ 95].
Vector Y k corresponds to the expression of the transcript, which is possibly regulated by transcription factors from X− k.
Transcription levels and breadth of expression negatively correlate with the length of introns and the size of primary transcript, which is likely due to the necessity to minimize metabolic costs of transcription for abundant mRNAs.
In the present study, we used quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) [ 21] to specifically quantify the CK19 transcript, which is considered to be relatively specific for epithelial cells in the feces of CRC patients.
My transcript, which is usually a mess of elipses, reads like it's been lifted off the page.
The entire transcript, which is very much worth reading, is available on the Fed's Web site.
The site of polyadenylation [ poly(A) site] marks the end of a transcript, which is also the end of a gene.
Specifically, our patient had an MLL-AF10 fusion transcript, which is rather rarely found among the large variety of the various MLL rearrangements [20].
Indeed, miR824 targets the AGL16 transcript, which is under miRNA pathway-dependent repression (Figure 2A).
The fusion between m-bcr and abl leads to a "large" transcript, which is present in 100% of examined patients with m-BCR Ph+ ALL [7].
Recent evidence suggests that its miRNAs are encoded by an intron of a non-protein coding Pol-II transcript which is mainly expressed in the placenta [4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com