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The SNPs located at exon regions were thus used as tags to distinguish two transcript structure variation sources: allelic variations and post-transcriptional alternative splicing.
This study analyzes the correlation between human transcript structure (in the context of AS) and fine-scale protein structural units (PUs) (fig. 1).
Further analyses indicated that transcript structure features tend to be preferred universally.
Any delineation of transcripts assumes prior knowledge of transcript structure.
Transcript structure variation comes from allelic variations and AS.
The association between transcript structure isoforms and SNPs indicated that more than 28% of transcript structure variation events were contributed by different gene alleles in A. gambiae.
Transcript structure variations (TSVs) are common in eukaryotic organisms [1], [2].
The ESTs in each group had the same transcript structure variation isoform.
The gene and transcript structure of bacteria and dinoflagellates are strikingly different.
About 28% of transcript structure variations were predicted from different gene alleles.
We used the new genome annotation to guide the analysis of the transcript structure variations.
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