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Our results indicate the existence of at least two unique isoforms of NEAT1: a widely expressed, abundant 4 kb transcript and a much larger (> 17 kb), less common transcript sharing a transcriptional start site, based on 5'-RLM-RACE and Northern analysis.
The identification of a transcript sharing sequence similarity with CD147 (basigin) (i.e. #23314) was another noteworthy finding.
In addition, no transcript sharing similarity to genes encoding the enzymes responsible for the conversion of AIR into thiamine monophosphate were identified at any time-point.
For all these sequences, RNA-seq experiments revealed a short non-coding (ncRNA) form and a long transcript sharing the same TSS, supporting a cis-regulatory mechanism.
However, ASPicDB suggests a mouse transcript sharing exactly the structure of NM_006624 (602 aa) and encoding a protein with the complete PHD finger domain.
PpCBM, a transcript sharing sequence homology with a peritrophic membrane chitin binding protein from the cabbage lopper Trichoplusia ni (AAR06266), was found to be 6.2-fold up-regulated exclusively in the post-moult stage when compared to intermoult.
Similar(53)
One transcript shared high sequence similarities with the evolutionarily conserved cellular repressor of E1A-stimulated genes (CREG).
For example, a transcript shared with other animal lineages but not non-metazoan eukaryotes or prokaryotes would be assigned to the metazoan ancestor.
We also investigated whether splicing patterns for transcripts sharing the same transcription start site (TSS) differ between normal and AD brain tissue (Table 8).
A list of 8462 sets of transcripts sharing a particular Gene Ontology term was generated by considering.
The transcripts sharing any exon are merged into a single TU.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com