Nevertheless, despite promoter enrichment, the majority of HIF-1-and HIF-2-binding sites (50% and 70% respectively) were still found to lie in excess of 2.5-kb from the promoter of an expressed transcript of any class (Fig 2B and C).
A proportion of reads did not map to an annotated transcript of any class.
The rice (Oryza sativa spp. japonica) genome contains 2,384 TF gene models, which represent the mRNA transcript of a locus, classed into 63 families.
Two human cDNA clones encoding alternative transcripts of a mu class GST have been detected but both are incomplete and thus unlikely to encode functional GSTs [ 32].
Both genes pairs encoded a class of long sense transcripts and a class of short sense transcripts that terminate within the same polyadenylation region as the antisense transcripts encoded by the opposite strand.
A corresponding up-regulation of the transcripts encoding invertases, a class of enzyme that catalyzes the breakdown of sucrose to constituting monosaccharides, was observed.
Natural antisense transcripts represent a class of regulatory RNA molecules, which are characterized by their complementary sequence to another RNA transcript.
This led us to question whether these early responding transcripts represent a class of genes not processed through the SL mechanism and under transcriptional control.
Our results showed that transcripts of class I and class II HDACs were increased once the differentiation was initiated and were kept at high levels in all stages, indicating that HDACs participate in the process of neural differentiation (see Additional file 1: Figure S1B).
Antisense transcripts make up a class of lncRNAs that are transcribed from the opposite DNA strand of the sense RNA transcripts with which they share sequence complementarity, and the existence of a long antisense transcript for core clock genes has also been reported in Neurospora and Antheraea pernyi (silkmoth).
