Thus, the up-regulated categories consisted of more unique transcripts in general than those that were down-regulated.
Non-protein-coding pri-miRNA transcripts are therefore significantly shorter than protein-coding transcripts in general, and particularly those that also express miRNAs.
In general, the dmRNAs demonstrate functional prevalences that are typical of the population of human transcripts in general, as judged from counting up Gene Ontology functional category annotations (Additional File 1).
This enrichment is not true of C. elegans GLD-1 targets, which, as for germline transcripts in general, are actually rarely X-linked (e.g., Fong et al. 2002; Reinke et al. 2004).
Althouggh such specificity was expected for testis and accessory gland tissue given their specialized functions, we found a large proportion of tissue-specific transcripts in general body tissue as well.
Although the destiny and regulatory significance of alternatively spliced PTC-harboring transcripts in general and in circadian genes in particular remain unclear, the discovery of widespread unproductive AS in plant circadian genes raises a question of whether alternatively spliced mRNA serve as regulators of the circadian clock.
Since 18S rRNA is a more globular structural form of RNA (and therefore likely subject to different degradative stresses or processes than mRNA), it is being increasingly thought of as a poor representative of linear transcripts in general (comment by Jim Wicks, Ph.D., PrimerDesign Ltd).
It is generally acknowledged that transcript databases in general, and EST databases in particular, contain contaminants of various kinds [17].
Since antidirectional transcripts require independent cis-acting regulation, predominance of these events over allele-specific antisense transcripts would suggest that antisense transcription in general is a functionally regulated process.
