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Data from subcutaneous adipose included in the current study suggest rs4731702 near KLF14 (7q32.3) is associated in trans with SLC7A10 expression, which supports SLC7A10 as an important trans adipose target associated with metabolic traits as previously suggested [ 73].
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A previous study on the trans-differentiation of marrow and adipose stem cells has also shown that the adipocyte differentiation of marrow stem cells results in the overmethylation of short transitional-CpG segments of the PPARG and CDKN2A genes but not long transitional-CpG segments of the MLH1 and RUNX3 genes [ 13].
Proportions of total CLA and cis-9, trans-11 CLA tended (P<0.10) to increase in muscle and adipose tissues owing to the inclusion of SA in the diet.
Blood fractions, serum, plasma, and erythrocytes are widely used in epidemiological studies to assess trans fatty acid intake but indicate short-term intake as compared to adipose tissue.
To assess the accuracy of measures of trans fats in studies that did not directly measure concentrations in blood or adipose tissues, we assessed the potential for misclassification.
Trans fatty acid levels in cheek epithelium correlated significantly with that in serum and adipose tissue.
Trans-10,cis-15 18:2 has been recently detected and characterized in digestive contents and meat and adipose tissue of ruminants, but its presence in milk and dairy products is hardly known.
Recently, Price et al. [ 12] analysed microarray gene expression data from blood and adipose samples of Icelandic family cohorts and began to partition the heritability into cis and trans components using a variance component model composed of polygenic effects estimated using identity by descent (IBD) for chromosome segments both proximal (cis) and distal (trans) to the gene of interest.
In addition to the cis-eQTLs, we detected 73 trans-eQTLs and the functional annotation of this group of genes using GeneNetwork resulted in the detection of (subcutaneous) adipose tissue as associated over-represented tissue (P = 6E−4).
adipose tissue-endothelial cells.
As Marianne Kirby explains, "'Fat' means adipose tissue.
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