However, HLM analysis revealed significant group differences in the trajectory of quality of life, such that women receiving PBRT exhibited a linear increase in quality of life over time after completion of radiation therapy; whereas women receiving WBRT showed a decreasing trajectory.
Little is known about the trajectory of quality of life (QoL) following a first episode of psychotic mania in bipolar disorder (BD).
This exploratory analysis is the first to describe the trajectory of quality of life at the end of life in such detail.
An ideal analysis would compare the likely trajectory of quality under each system, however as an experimental comparison is not feasible, we must base this on fragmented evidence.
There is growing recognition of the unique and important role ED care providers can play in supporting early palliative care interventions along a patient's disease trajectory, promoting quality of life, as well as reducing treatment costs [ 50- 54].
It is possible that the increasing trajectory in quality of life we observed for women receiving PBRT may be related to lower fatigue, as previous findings confirm that cancer-related fatigue significantly interferes with the course of daily living, diminishing quality of life [ 10, 63].
This result points either to rather unpredictable trajectories of quality development or the further need of improvement of the observational tool.
EMMACE-3 is a contemporary longitudinal study of detailed trajectories of quality of healthcare and outcomes for ACS.
Thus whether trajectories of quality of life form a relentless march of decline or one with a peak is as yet undecided.
