Your English writing platform
Discover LudwigExact(2)
However, unlike the models mentioned above, my modeling approach allowed to simulate and track the continuous trajectories of expression patterns in one-dimensional virtual syncytial embryos, over developmentally relevant time scales.
Similarly, members of the chromobox homolog (CBX) gene family showed opposite trajectories of expression (Fig. 4C) with CBX1A/B, CBX2, and CBX5 in cluster 1 and CBX7A/B and CBX8A/B in clusters 2 and 6.
Similar(58)
Taken together, our results indicate that postnatal ketanserin treatment prevents the altered regulation of specific genes known to be perturbed in the adult PFC following MS. We next sought to examine whether postnatal treatment with the 5-HT2 receptor antagonist ketanserin during MS influences the trajectory of expression of 5-HT2A and 5-HT2C receptors within the PFC.
In sequencing two anatomically interconnected regions at the same time from the same subjects, we were able to directly compare the magnitude and trajectory of expression in juvenile and mature animals at key time points before and after the onset of hearing.
Our task was to learn the networks from two types of data, namely gene expression profiles in deletion strains (the 'deletion data') and time series trajectories of gene expression after some initial perturbation (the 'perturbation data').
Considerable effort has been devoted to characterizing patterns of natural variation in and the evolutionary trajectories of gene expression levels both within and between species [1] [9].
Furthermore, the temporal trajectories of this expression is consistent with the known mechanisms of such signaling.
Our approach to study trajectories of gene expression also uncovered consistent patterns in multiple genes pertaining to the MAPKKK (Mitogen-activated protein Kinase Kinase Kinase) cascade.
According to [ 41- 43], in microarray data analysis, genes are considered to be in the same cluster if their trajectory patterns of expression levels are similar across a set of conditions.
Overall our findings pinpoint genes in species from disparate environments that are on different evolutionary trajectories in terms of expression levels and/or nucleotide sequence.
Validation of sequencing was accomplished by in situ hybridization (ISH) of 4 genes (Gapdh, Slc32a1, Slc17a6, Slc17a7) in A1 and MG, also profiled in a related study of their maturational trajectories, regional patterns of expression, and co-expression within single neurons.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com