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These QTLs were also detected with single trait analysis.
Total heritability was estimated by genome-wide complex trait analysis.
The Trait Analysis by Association Evolution and Linkage (TASSEL) program (Bradbury et al. 2007) was used for the association analysis.
We aimed to establish the heritability of glycaemic response to metformin using the genome-wide complex trait analysis (GCTA) method.
The different topics include genome-wide association studies, genome-wide complex trait analysis, copy number variations, and epigenetic analyses.
We present novel approaches to complex trait analysis that make as complete use of marker information as is possible.
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QTLs detected by single-trait analyses were mostly detected also in multi-trait analysis except for four minor ones (Additional file 1: Table S6).
Fig. 4 Marker-trait analysis of the random subpopulation BC3F2-LQ96 derived from BC3F1-22F01 using Kongyu 131 as the recurrent parent and GKBR as the donor parent.
However, a combined multi-trait analysis can be more powerful than a collection of single-trait analyses (Malosetti et al. 2008).
Multi-trait analysis is shown in Table 5.
Multiple-trait analysis of the clustered traits tended to work better than single-trait analysis of the principal component variables but seemed to be a compromise between single-trait analysis and multitrait analysis of all 16 traits.
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