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All retrieved abstracts were screened for relevance by a trained reviewer.
Assessment by a clinician or trained reviewer is one standard diagnostic methodology for making a disease determination from such images.
Standard assessment of lens images is done using semi-qualitative classification schemes involving a trained reviewer and a standardized scale of severity [ 12- 18].
We hypothesized that a CAD system that assisted a trained reviewer could reduce measurement error and would be feasible to implement with standard software.
From our simulation study we found that the CAD algorithm outperformed the trained reviewer in estimating cataract severity from images with mild to moderate cataract involvement.
Digital retroillumination images from the Salisbury Eye Evaluation (SEE) Study [ 29] were used to train the CAD system and parameter values were determined empirically based on performance in identifying opacities (as assessed by a trained reviewer) in the SEE dataset of 601 right eye lens images and 603 left eye lens images.
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Centrally trained reviewers reviewed medical records for each participant using standardized data collection methods to abstract process of care measures, clinical parameters, and laboratory values.
Trained reviewers entered, reviewed, and coded the information contained in the returned questionnaire into a database using the software Microsoft Access 2010.
Medical records were reviewed by centrally trained reviewers.
30 The patient files will be systematically reviewed by two independent and trained reviewers; one from the research team and one representative from the specific department in order to secure validity and consistency in the measurement of performance.
Using this article as an example helped us to illustrate that, even though each step of our approach might be well known by statistically trained reviewers or readers, strictly applying this four-step procedure could have provided some important warning signals when apprising Boldt's manuscript.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com