Sentence examples for trail specifically from inspiring English sources

Initially it was shown that TRAIL specifically induces tumour cell apoptosis and tumour regression in nude mice, even when applied as single agent [ 6, 7].

The cytokines, FasL, TNF or TRAIL, specifically bind to their related receptors present on the hepatocyte surface, namely Fas, TNF receptor type 1 (TNF-R1, p55/65, CD120a) or TRAIL receptor type 1 (TRAIL-R1, DR4) and type 2 (TRAIL-R2, DR5), respectively (Yoon and Gores 2002; Schattenberg et al. 2006).

The White House Inn (178 Route 9, East Wilmington; 800-541 2135) has trails specifically for snowshoeing.

One rapidly developing approach for mitigating these conflicts is the development of maintained winter trails specifically for fat bikes.

Cross-country skiing can be done in open fields within the park, though the park does not maintain any trails specifically for skiing, and does not rent ski equipment.

Also, in many towns there are clubs that will build and maintain trails specifically for riding.

The antitumoral effect of TRAIL was specifically mediated by membrane-bound TRAIL via the death receptor pathway, and enhanced the therapeutic potential of cytotoxic drugs.

We examined a selection of tumour cell lines, (including three leukemic cell lines) looking for evidence of synergy between ATO and TRAIL and specifically, to identify the cellular mechanisms underlying this effect.

In the preface to his new book The Watchers of the Trails, Roberts specifically responded to Burroughs' criticism by carefully pointing out that his stories were "avowedly fiction".

In this respect, the capability of TRAIL-R1 and TRAIL-R4 to specifically interact with TRAIL-R2 in the nucleus also raises the question of the capacity of these receptors to modulate the nuclear functions of TRAIL-R2.

Hence, we set out to develop MSCs that express and secrete TRAIL variants that specifically target TRAIL-R2 to achieve greater apoptosis induction in 5-FU-treated tumor cells.