Sentence examples for trail resulting from inspiring English sources

Some anticancer agents, in addition to UV radiation, have been shown to overcome the resistance to TRAIL, resulting in a synergistic effect with TRAIL.

During the 2008 race, competitors started in -40 F temperatures in Fairbanks and then faced winds of 25 mph on the trail, resulting in severe wind chills.

Consistent with this, deletion of IKKγ in mouse hepatocytes caused hypersensitivity to TRAIL, resulting in massive liver damage [38].

Taken together, these data suggest that IPS-1 induces the type I IFN, which in turn induce the pro-apoptotic gene TRAIL, resulting in anticancer activity.

Owing to caspase-8 silencing, SH-EP-shC8 and SK-N-AS-shC8 cells became fully resistant to TRAIL, resulting in apoptosis resistance, as demonstrated in SH-EP-shC8 cells.

In addition, activation of RLRs induces the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), resulting in the initiation of the extrinsic apoptotic pathway in an autocrine manner.

Interestingly, the addition of ABT-737 to TRAIL resulted in a longer half-life of tBid compared with treatment with TRAIL alone.

We transported our lazy son Charlie on a tagalong (second time lucky!) after a previous attempt to get the lad pedalling on a steep forest trail resulted in downed tools, small arms crossed resolutely as he sat stubbornly in the mud.

Sequential treatment with etoposide and TRAIL resulted in a synergistically induced cell death in the two resistant lines (MIT7-xL and MIT16) but not MIT8, as assessed by WST-8 assay.

For example, the combination of vorinostat and TRAIL resulted in significant growth inhibition when compared with either treatment alone in mice bearing TRAIL-resistant tumor xenografts [ 28].

Notably, exposure to TRAIL resulted in the recruitment of pro-caspase 8 and FADD to the lipid rafts in R1 cells.