Sentence examples for trail is due from inspiring English sources

Hence, the synergistic effect of CDK9 inhibition and TRAIL is due to a dual mechanism: downregulation of cFlip enables caspase-8 activation at the DISC and downregulation of Mcl-1 facilitates activation of the mitochondrial apoptosis pathway for enhanced caspase-9 and, ultimately, caspase-3 activation.

Whether the greater loss in activity of biotin-NHS-TRAIL is due to the relative higher extent of derivatization or to modifications of lysine residues in the activity domains of protein can not be concluded from our data.

Enhanced TRAIL sensitivity is due to TRAIL receptor up-regulation induced by gp120.

It is found that the larger noise reduction achieved by the iron-shaped trailing-edge serration is due to the mitigation of the scattered noise at the root.

The design of the device has also not yet been finalized but Geeksphone is emphasizing fashion as another priority for its first wearable — which will arrive in the market in the wake of Apple's also fashion-focused (and long trailed) Apple Watch, which is due to ship in April.

The reason for this spectrum of response to TRAIL-R activation is due to the complex downstream regulation of the cell death pathway.

Together, this set of data indicates that ABT-737-mediated sensitization of glioblastoma cells toward TRAIL is not due to changes in TRAIL receptor expression, formation of the TRAIL DISC or complex II assembly.

To exclude the possibility that the H. pylori-induced sensitivity to TRAIL in gastric epithelial cell lines is due to upregulation of TRAIL DRs, we further examined the expression of TRAIL receptors before and after interaction with H. pylori.

For its forthcoming iOS 12 update — which was trailed at WWDC, and is due out this fall — Apple says the release will "double down" on performance, slating a slew of refinements, bug fixes and optimizations incoming.

It is therefore likely that the TRAIL resistance in these lines is due to an intracellular factor inhibiting the death signal.

These data suggest that the stimulation of TRAIL-induced apoptosis by salubrinal is due, at least in part, to inhibition of eIF2 α dephosphorylation.