Sentence examples for trail function from inspiring English sources

Analysis of lung metastasis revealed that blocking TRAIL function significantly increased CT26 tumor cell metastasis rate (p<0.001)(Fig. 5D).

Use of perforin-deficient pfpCTLs and Fas-resistant CT26 tumor cells will eliminate the function of perforin and Fas/FasL effector mechanisms of the CTLs, thus reducing the CTL cytotoxicity background for optimal TRAIL function evaluation.

It is clear that blocking TRAIL function significantly decreased CTL-mediated tumor rejection efficacy (p = 0.03)(Fig. 7B), suggesting that tumor-specific CTLs at least partially use TRAIL to suppress colon carcinoma development in vivo.

In NOD mice, blocking TRAIL function by a soluble TRAIL receptor increased the onset of diabetes.

A potential solution to increase specific activity and bioavailability is the combination of TRAIL function with tumor targeting.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) functions as a cytokine to selectively kill various cancer cells without toxicity to most normal cells [ 1, 2].

Indeed, TRAIL functions as an antiviral protein [ 13, 72] by inducing cell death in infected cells via the extrinsic pathway but can also induce immunosuppression.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) functions as a cytokine to selectively kill various cancer cells without toxicity to most normal cells.

In addition to a possible TRAIL-sequestering function, TRAIL-R4 might impair TRAIL-induced apoptosis by forming inactive hetero-complexes with TRAIL-R2, and/or by triggering anti-apoptotic signaling pathways such as NF- κB and PKB/AKT.

Also called the proapoptotic cytokine TNF-related apoptosis-inducing ligand or TRAIL, its function in ischemia remains to be clarified.

I first met Musco a few months ago on one of my regular visits to Mountain Lake Park, a lakeside San Francisco park with a Parcourse fitness trail which functions as my personal outdoor gymnasium.