Sadarangani et al. [ 5] describe the positive response of endometrium and endometrial cancer cell lines to TRAIL, and Llobelt et al. [ 30] demonstrate that endometrial cancer cells, primarily insensitive to TRAIL, can be sensitized to the ligand after administration of chemotherapeutics.
They also show that the increased sensitivity to TRAIL can be recapitulated in vitro, and therefore in vivo selection pressures are not necessarily required for the acquisition of TRAIL sensitivity.
At high tide the trail can be flooded.
The trail can be divided into two areas: Lexington and Bardstown.
But the trail can be reached from parking lots and connecting trails throughout the Catskills.
Compared with your average freeway, the pace of building a trail can be glacial.
While outdoor exhibits rotate seasonally, the Carell Woodland Sculpture Trail can be enjoyed anytime.
Free blacks, who left a paper trail, can be traced more easily.
The entire length of the trail can be walked, and many segments are open to bicycles and horses as well.
Jean-Pierre, however, is leaving us here: we've decided to see if the trail can be finished without a guide.
The trail can be reached from parking areas at the monument or near the interpretive center, off Route 23.
