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Today, Virgin Galactic confirmed it will complete its second spaceship "deliberately and with determination" despite what it described as a "tragic setback".
Aside from generally slow growth, the spread of AIDS has been a tragic setback, reducing longevity significantly in many African nations.
While Mr. Lucero's killing was feared to be part of a pattern of anti-Hispanic violence in Suffolk County, the attack on Mr. Sucuzhañay was seen as a tragic setback in an increasingly multicultural pocket of Brooklyn.
"The secretary general is concerned about the emerging pattern of killings of high profile personalities in Guinea-Bissau," the United Nations said in a statement, adding that "these criminal acts are a tragic setback for efforts to restore the rule of law and democratic processes in the country".
The project suffered a tragic setback earlier this year when Philip Langsdale, the DWP's chief information officer, died four months after taking over responsibility for it.
But Hasui carried on producing prints despite that tragic setback, much to the benefit of the Japanese printmaking tradition.
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"Such tragic setbacks must not weaken our determination or divert us from our commitment to peace and reconciliation in Afghanistan," he said in a statement.
While most hard-working people are getting ahead, a small but not insignificant number will be left behind or will encounter tragic setbacks that leave them penniless and helpless.
But gene therapies have had tragic setbacks.
First, we are continuing to see a huge amount of interest from investors to capitalise on the development and trajectory of self-driving services: despite some of the tragic setbacks we've seen, many have firmly planted autonomous technology into the category of "when", not "if".
At that point I wasn't certain what the story was going to be, but I liked the idea of exploring what goes on behind the glitz and glamour that causes so many young actors to suffer such tragic setbacks and downfalls.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com