It is not clear how planar-polarised E-cad trafficking would contribute to formation of a regular hexagonal array of cells, as removing E-cad from proximodistal distal junctions might be expected to cause shrinkage of these junctions at the expense of anteroposterior junctions.
It is therefore possible that in the kidney, the effect of disrupting ATMIN is to disturb the cytoplasmic functions of DYNLL1 and thereby disrupt planar polarity pathway functions (either protein trafficking and/or orientation of mitosis).
The network and planar K-function methods are applied to traffic accident data to illustrate the risk of false positive detection associated with the use of a statistic designed for a planar space to analyze a network-constrained phenomenon.
Related roles in neoplasia have been identified in mammals, with mammalian Scrib shown to play roles in a variety of cellular processes including the establishment of apical basal and planar cell polarity, migration, proliferation, differentiation, and vesicle trafficking.
Defining the role of F-actin in planar polarity and CE is further complicated by the observations that Cofilin proteins are essential for correct trafficking of PCP components (Mahaffey et al., 2013).
Although Src kinase is a known modulator of E-cad trafficking in the Drosophila embryo (Takahashi et al., 2005; Shindo et al., 2008), the significance of its planar-polarised distribution is unclear, as loss of core pathway function did not affect the distribution of Src, but did block the planar-polarised distribution of E-cad.
A planar image seems to become three-dimensional.
Both are planar and rugged.
"Different colors articulated the planar composition of interior walls," Raul Barreneche writes in Interior Design.
Planar is consolidating production of its electroluminescent display panels into a single factory in Espoo, Finland.
