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The trafficking not only results in higher prices but also deprives the government of desperately needed revenue.
Understanding the regulatory mechanisms of nuclear cytoplasmic trafficking not only provides important information about cellular processes, but also is of use for developing specific inhibitors for transport pathways.
Further, we recently discovered that in budding yeast, vesicle trafficking not only controls Cdc42 localization and function as previously demonstrated, but at least one of the 3 Cdc42 GAPs, Bem3.
One possible explanation about the significant apoptotic changes in the ONL suggests that disruption of OPTN Rab8 complex may affect the trafficking not only in the RGCs but also in the photoreceptors.
Since only agonist ligands seem to promote receptor internalization, also fluorescent agonistic ligands are a valuable tool for the investigation of receptor trafficking, not only in living cell culture studies but also in living neuronal cells.
Our data raise the concern that treatment of humans with compounds like natalizumab that interfere with T cell trafficking not only by quantitatively reducing the migration of T cells into the CNS but also by selectively targeting distinct T cell subsets may evoke serious deficiencies in cellular immune responses at privileged anatomical sites like the CNS.
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Then traffic not only plateaued, it fell.
"Decreasing traffic not only decreases traffic jams but increases cardiovascular health.
"Foot traffic not only could be foot traffic but animal traffic, too," Mr. Wachtel said.
Computer modelling has made it possible to study traffic not only as a physical system but as a social system, and several notable papers have appeared that explore the relationship between driver behavior and traffic jams.
As engineers continued to forecast traffic growth in line with historic averages – up, up and yet farther up, to an eventual "carpocalypse" – actual traffic not only fell short of projections, in many places it just plain fell.
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