Sentence examples for traffic steps from inspiring English sources

VAMP7, which is otherwise known as TI-VAMP [ 42], appears to be involved in multiple SNARE complexes in various traffic steps in different cell types.

For instance, the endoplasmic reticulum (ER) and the plasma membrane (PM) cannot fuse directly, but they are functionally connected through multiple membrane traffic steps, a time-consuming process.

These findings suggest that VAMP7 may associate with a variety of other SNARE partners to function in multiple membrane traffic steps which may in part be cell type-specific [ 42].

Membrane traffic steps can be defined by the nature of the SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) complex that underlies the fusion of vesicles with their target membrane.

Unlike other traffic steps, no coat proteins have been identified, and there may be redundant pathways to the plasma membrane, especially in polarized cell types such as epithelia and neurons where proteins need to be delivered to different parts of the cell surface.

Thus, any impairment of the ER-to-Golgi traffic step might prevent SFKs activation.

The transport protein particle (TRAPP) complexes are involved in the tethering process at different trafficking steps of vesicle transport.

SNAREs seem to mediate membrane fusion in all of the trafficking steps of the secretory pathway.

These data suggest that Staufen does not play a role in the early trafficking steps of osk transport, but rather in the terminal stages of transport.

On the other hand, Clarke et al. [17] and Melke et al. [18] proposed the models for the Smad nucleocytoplasmic shuttling and Smad phosphorylation response to the TGF-β signal without considering the receptor trafficking steps.

Together these studies suggest that aSyn causes defects in multiple vesicle trafficking steps.