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This envelope contains nuclear pore complexes (NPCs), which mediate the traffic of molecules between the two compartments.
Mesothelin may have the function of regulating the traffic of molecules and cells into and out of the peritoneal cavity (Bera and Pastan, 2000).
However, less is known of the precise location of chromosomes and their relationship with the internal nuclear membrane and nuclear pores through which the traffic of molecules is made.
While the BBB separates or controls the traffic of molecules from the blood to the cerebral interstitial fluid, the BCSFB is a discontinuity in the circulation between the blood and cerebrospinal fluid (CSF).
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Cucurbits are also an important model species in many key areas of plant research, including sex determination [2], [3], [67], fruit maturation [4], [5] and the investigation of vascular trafficking of molecules [6], [7].
These proteins have a wide spectrum of functions, such as degradation of proteins in the retinal pigmented epithelium (RPE), ionic interchange, trafficking of molecules in the ribbon synapse of photoreceptors and many others.
Cross talk among different classes of brain cells is also essential to generate the blood-brain barrier (BBB), which then maintains brain internal milieu, by controlling trafficking of molecules and ions between the brain and the blood [ 28].
These proteins are involved in retinal functions, but they can also play other roles such as degradation of proteins in the retinal pigment epithelium, and ionic interchange or trafficking of molecules in the ribbon synapse of photoreceptors.
It is presumed that dysregulated astrocyte hemichannel activity leads to the disruption of homoeostatic ion and neurotransmitter gradients (i.e. K+ and glutamate respectively) via the bi-directional trafficking of molecules through open hemichannels (Giaume et al., 2010).
Most importantly, they add further arguments to the idea that the trafficking of molecules between neurons and astrocytes underlies a broad functional, rather than strictly energetic partnership (see, e.g. [ 65]).
On the other hand CPNs can be delivered into the culture medium and their intrinsic fluorescence can be relied on to visually monitor the trafficking of molecules within the endocytic pathway to obtain new information about these pathways.
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