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However, neither the traffic mechanisms of KIAA0319 nor the motifs in its sequence driving this traffic were known.
Diffusion-based transport via inter-compartment continuities remains the least explored and understood of the traffic mechanisms.
For phagocytosis, a cell requires complex machinery of membrane traffic mechanisms: an endoplasmic reticulum, Golgi, actin/tubulin cytoskeleton, cytokinesis, vesicle fusion mechanisms, phagosome formation, exocytosis, etc.
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In this regard, recently, different strategies are proposed to control traffic mechanism automatically [1 3].
Highly secreting cells, including certain cancer lines, might preferentially use one rather than another traffic mechanism.
In this paper, we elucidate how the motor components coordinate to revolve the dsDNA, ensure a one-way traffic mechanism, and continuously advance dsDNA without reversing.
The activity of these kinases is regulated by phosphorylation/dephosphorylation, subcellular traffic mechanism, association with cyclin proteins and with specific cdk-inhibitors, and by proteolytic degradation (Sherr and Roberts, 1999).
Polar growth at the pollen tube tip is believed to result from secretion of materials by membrane trafficking mechanisms.
The difference in this gradient gives credence to particle-trafficking mechanisms via structural engulfment rather than hypothesis of Fickian diffusion across the intracellular and paracellular routes.
Flotillins appear to play a role in cellular uptake or trafficking mechanisms of NPs and are discussed as indicators for clathrin- or caveolae-independent uptake mechanisms.
Further research needs to be done in order to better understand stem cells mechanism of action in regard to their immunomodulatory, differentiating, paracrine, regenerative, and anti-inflammatory abilities as well as their cellular trafficking mechanisms.
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