Sentence examples for traffic and function from inspiring English sources

However, the validation of compounds in stable organotypic cell systems at an early stage is essential, as immortalized cell lines do not show the physiological characteristics of the relevant respiratory, intestinal, pancreatic, or bile duct epithelia, including regulation of CFTR expression, traffic, and function, in particular in the context of inflammation and tissue injury responses.

Thus, minocycline treatment reduces the expression of several markers critical for monocyte traffic and function at late stage of infection, and in the case of HLA-DR is reduced below that found prior to minocycline treatment.

The proposed sensing interface using phosphonic moieties as functional group holds promise to generally estimate metal accumulation, trafficking, and function or toxicity in living systems.

Together, alterations in the intestinal physiology triggered for example by inflammation can exert adverse effects on the trafficking and function of SI.

Here we discuss how the tumor and its microenvironment influences T cell trafficking and function with a focus on melanoma, and pancreatic and ovarian cancer, and discuss how scientific advances may help overcome these hurdles.

Here we examine the expression, trafficking and function of each variant in detail.

We pursue a number of approaches to characterise the expression, trafficking, and function of the two isoforms of ULBP5/RAET1G.

To further understand the range of responses of AR trafficking and function potential mechanisms, we examined several environmental compounds previously characterized as having anti-androgenic activity.

Palmitoyltransferases make interesting drug targets for therapeutic intervention, mainly because of their involvement in the modification of oncoproteins [21] and their role in modulating neuronal trafficking and function [6], [7], [9].

However, we cannot exclude that a lack of glycosylation itself might impair trafficking and function.

The present study has illuminated the trafficking and function of a Ca2+-sensitive adenylyl cyclase.