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Although normally expressed in the gastrointestinal tract, expression of Brk is not detected in the normal mammary gland [ 16, 19].
In the gastrointestinal tract, expression of COL1A2 may be associated with endothelial-to-mesenchymal transition [ 23].
For example, in the gastrointestinal tract, expression of Snail, Slug, Twist, Zeb1 and Zeb2 has been associated with unfavourable survival outcomes in patients with oesophageal (Uchikado et al, 2005), gastric (Kim et al, 2009; Ru et al, 2011; Dai et al, 2012), colorectal (Shioiri et al, 2006; Kahlert et al, 2011) or pancreatic cancer (Kurahara et al, 2012).
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It is currently unclear why such variability is observed in flies; however CTG tract sizes, expression levels and context of expression may all contribute to the differences in the observed phenotypes.
In the tammar gastrointestinal tract, weak expression was found in intestine while much stronger expression was observed in stomach and caecum, showing tissue-specific expression patterns.
Lef-1 is normally not expressed in the intestinal tract but expression has been detected in CRC and several CRC cell lines, together with Tcf-4 and Tcf-1 [58] [58].
AQP6 mRNA was expressed in all the portions of the rat gastrointestinal tract, although expression levels varied between samples (Fig. 1).
Since JCV Mad-1 DNA can be found throughout the gastrointestinal tract the expression of T-Ag protein is believed to be a more suitable method for understanding oncogenic role of JCV in human cancers [16].
Histology revealed an adenocarcinoma of the biliary tract with expression of epithelial growth factor receptor.
Within the female reproductive tract GGT expression was found in endometrial and endocervical glands.
Within the GI tract, colonic expression is the greatest and gastric the lowest.
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