The major inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are both debilitating disorders of the gastrointestinal tract, characterized by a dysregulated immune response to unknown environmental triggers.
Hirschsprung's disease (HD) is a congenital malformation of the gastrointestinal tract characterized by the absence of the distal enteric nervous system.
Mayer Rokitansky Kuster–Hauser (MRKH) syndrome is a disorder of development of the female genital tract, characterized by the absence of the upper portion of the vagina, an absent or hypoplastic uterus, and normal or hypoplastic fallopian tubes.
Antibiotic therapy for a direct administration to the lung in cystic fibrosis patients has to provide suitable availability, possibly in the lower respiratory tract, characterized by the presence of thick secretions.
ratio, compressed matrix tablets, potentially able to deliver the model drug, prednisolone, to sites in the GI tract characterized by specific pHs, such as the jejunum or the ileum.
Irritable Bowel Syndrome (IBS) is a highly prevalent functional disorder of the gastrointestinal tract characterized by the presence of abdominal pain or discomfort, an alteration in bowel habit and the absence of reproducible biomarkers [1], [2].
