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Tracking alterations in neuronal function in HIV patients receiving MVC intensification by neurocognitive assessments and neuroimaging techniques such as magnetic resonance spectroscopy will confirm whether CCR5 inhibition is neuroprotective in the clinical setting of HAND.
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But ATLAS can also track alterations in forest growth, a key indicator of carbon gain or loss.
To examine phenotype progression over time, we tracked alterations in the plantaris nerve, as this distal nerve is a sensitive indicator of nerve changes in mouse models of hereditary motor and sensory neuropathies (Frei et al., 1999; our unpublished observations).
Moreover, we have developed microfocus mapping techniques to track alteration in bone thin sections across microscale areas such as individual osteons.
First, the feasibility of tracking structural alterations in the components of individual corneocytes is demonstrated.
Transcriptome and proteome profiling was used to track macromolecular alterations in exposed and shielded organs.
Natriuretic peptides closely track acute alterations in LAP and may be utilized for guiding HF therapy, but because the current assay technology requires a visit to the clinic, natriuretic peptides cannot be used for altering daily prescriptions using a physician-directed patient self-management therapeutic paradigm.
Recent advances in genetic engineering of mouse models allow tracking of cytogenetic alterations in living cells, from the time of irradiation and throughout tumour ontogenesis.
Coincident with hypomyelination, an extensive gliosis was seen in both the cortex and white matter tracks, suggesting alterations in cell fate due to changes in mTOR activity in oligodendrocyte precursors.
Dynamic tracking of genetic alterations in PDXs as well as patients during treatment and after relapse is feasible by sequencing circulating cell-free tumor DNA and analyzing circulating tumor cells.
Bridge strengthening, ballast and track alterations, locomotive alterations, locomotive driver training changes.
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