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Microdissection and visualization of individual hair follicles for lineage tracing studies.
Transganglionic tracing studies have revealed the detailed somatotopy of primary afferent terminal fields in brainstem and spinal cord.
One approach to address these open questions is to conduct in vivo fate tracing studies at appropriate developmental stages.
Tracing studies are rewarding because they require close collaboration between neurobiologists and virologists.
Anterograde52, 63, 64 and retrograde51, 52, 65 tracing studies in the rat implicate the periambigual parvicellular reticular formation as the presumptive location of ventral "switching" interneurons.
Using resting-state fMRI, Marquand et al. estimate striatal connection topographies in humans and find correspondence with those predicted from primate tracing studies.
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The detailed shoot used measurements of Scots Pine shoots used in previous ray-tracing studies.
Lineage-tracing studies, on the other hand, suggest that both basal and luminal cell layers in adult murine prostate contain lineage-restricted stem/progenitor cells9,10 although primitive SCs reside in the basal layer10.
Recent lineage-tracing studies indicated that zebrafish fin ray bone regenerates through the dedifferentiation and proliferation of spared osteoblasts, with limited if any contribution from other cell types.
Under growth factor withdrawal conditions, the proportion of asymmetric CD133 divisions increased, congruent with the increase in asymmetric cell divisions observed in the lineage-tracing studies.
PTF1α is required for exocrine cell differentiation, and lineage-tracing studies show that Ptf1α-expressing cells give rise to all pancreatic cell lineages [58], [59].
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