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Species identification and/or classification from a single cell has an ultimate value for various purposes: genome analysis of precious specimens using only a minute fraction of the available sample or tracing alterations in the genome of somatic cells (e.g., differences between the genomes of the cells from the brain and heart).
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Tracing microsatellite alterations in follow-up sera of patients with different cancer entities and investigating their clinical significance has previously been described in several studies [ 27, 28].
Due to these unique properties, urothelial tumours provide a good model for the clonal analysis and chronological tracing of genetic alterations in human cancer.
A larger, more recent cross-sectional observational study which focused on trace metal alterations in renal patients and possible associations with bone diseases [ 91] did not find a higher absolute bone magnesium content in these patients, though an increased magnesium-to-calcium ratio was found compared with controls.
Thus, Se may act as an antitumoural agent although more studies are needed to investigate the actual role of antioxidants and their possible relationships with trace elements alterations in the pathogenesis of breast cancer (Bock et al, 1991; Gerber et al, 1996).
The ban on hormone-altering alterations in baby bottles.
Through proteomics it has been possible to establish that certain diseases can be traced from alterations of certain proteins in plasma [ 2].
Figure 1 depicts a representative tracing of beat-to-beat alterations in developed force (Fdev).
Given the demonstration of mitochondrial UC dysfunction by enzymology, stable isotopic tracing was employed to assess alterations in ureagenesis.
Many age-related neurochemical changes can be traced to structural and functional alterations in neuronal membranes [ 11].
The changes in the RBC volume, surface area, aspect ratio, and hemoglobin composition were used to trace the morphological and compositional alterations in the infected RBCs occurring with parasites' development and to provide insights into parasite-host interactions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com