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They then used fluorescent antibodies that bind specifically to the protein to trace the virus's interactions with various kinds of cultured cells.
They also attached a human gene to it that produces pro-enkephalin, a natural pain-blocking peptide, as well as a second gene that produces a blue dye, to trace the virus's path under a microscope.
To trace the virus in its path through the mucosa, human colonic explants were exposed for 30 min to R5 HIV-1AD8 or HIV-1J6363 or medium as control.
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Other studies have traced the virus and its effects in people who were infected through contaminated blood about two decades ago.
They initially became targets when investigators traced the virus to a computer in their apartment, but when it was raided on Monday the computer had been removed.
Investigators traced the virus to a ramshackle inner-city apartment where Mr. de Guzman was living with his sister and her boyfriend while attending a local computer college.
Prosecutors said they had focused on the couple because they had traced the virus to a PC in their apartment in Pandacan, a lower-middle-class area in Manila.
Subsequent work traced the virus back to a precursor virus that infects wild geese but is relatively benign.
Several teams have already traced the virus circulating in Brazil and elsewhere in South America to a strain of Zika that had been quietly circulating in Southeast Asia for decades.
In the hope of further understanding Zika's spread, Valderramos and her team traced the virus' genetic makeup over several decades, countries and organisms, using samples from both humans and mosquitoes.
In 2003, US officials identified several human monkeypox cases and traced the virus exposure to infected captive prairie dogs.
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