Sentence examples for tpl 1 from inspiring English sources
Exposure of HCT116-E6 cells to TPL (1 and 2.5 mM) for 24 h does not induce any variations in p53 expression, while a dose-dependent increase in p21 expression can be observed following treatment with the nitroxide.
Figure 5 shows that 24 h exposure to TPL (1 and 2.5 mM) induces a dose-dependent increase in both p53 and in p21 levels in HCT116 cells, whereas in HT29 cell line TPL treatment only induces a dose-dependent increase in p21 expression.
New 20RK270 engines benefited from two TPL 65 turbochargers, the latest generation from ABB Turbo Systems.
To further determine the combination effect of TPL and IDA, LSC-like cells were exposed to IDA (27 nM) with or without TPL (5 nM) for 24 h.
LSC-like cells were also exposed to a series of concentrations of IDA with or without TPL (IC20 5.0 nM).
As shown in Figures 3f and g, TPL in combination with IDA drastically reduced the colonies formed by the LSC-like cells compared with TPL alone, IDA alone and the negative control (-VE: 2097.3±106.07/well; TPL: 1387.7±40.05/well; IDA: 1252±46.87/well; TPL+IDA: 211±93.18/well, P=0.000).
Univariate analysis revealed BMI (p=.05), hematocrit before TPL (p=.014) and MELD score (p=.014) as preoperative risk factors for RRT after transplantation.
The expression of p53 and p21, before and after 1 h exposure to DOX (1.0 and 10 μM) followed by 23 h incubation in drug-free medium, or after 24 h exposure to TPL (1.0 and 2.5 mM), was evaluated by Western blot analysis of total protein extracts (lysis buffer: NP40 1%, leupeptin 10 μg/ml and aprotinin 10 μg/ml in TBS).
Ten reference genes [ 14-3-3ε 14-3-3ε 14-3-3εAppleIF-1A, l (3)02640, Rap2l, RpL32, Su (Tpl) and αTub84B] were measured for data-speCyp1c normalization (Ling and SalvatElav, 2011c).
Expression plasmids encoding His6-tagged TPL-2 and TPL-2D270A (NCBI RefSeq NP_001231063.1), FLAG-tagged human TPL-2 and TPL-230 397, TPL-230 397nandy StrepII-tagged ABIN-2 (NCBI RefSeq NP_077285.3) were generated by PCR amplification and subcloning into the pCDNA3 vector (Life Technologies).
Lang, V. et al. ABIN-2 forms a ternary complex with TPL-2 and NF-κB1 p105 and is essential for TPL-2 protein stability.
