Articles can incorporate: normal values, abnormal reactions, human, veterinary and zoological data, diagnostic and toxicological changes, experimental studies (both in vivo and in vitro) and new technology and its impact on diagnosis and disease control.
With emphasis on toxicological properties, experimental studies have highlighted the detrimental effects of different Te compounds in several tissues including liver, kidney, and blood [ 9– 11].
The Society of Toxicology (SOT) sponsored a series of panels, seminars, and workshops to help catalyze and improve the design and conduct of experimental toxicological research to better inform risk assessors and decision makers.
The null results are also coherent with toxicological data from experimental animal studies.
Toxicological studies in experimental animals (rat and dog) showed that up to 60 mg/kg/day wogonin had no organ toxicity when intravenously administered for 90 days.
The possibility that environmental xenobiotics could affect social success of an individual is concerning and calls for an introduction of a social dimension in experimental toxicological research.
Toxicological, epidemiological and experimental studies [ 12- 15] established that excess of these metals can disrupt body functions and have pathogenic effects in human respiratory organs, kidney and skin and affect sexual and neurological development and functions.
We reviewed toxicological studies, both experimental and epidemiological, that appeared in international literature in the period 1990-1997 and included both leaded and unleaded gasolines as well as their components and additives.
The Navigation Guide systematic review methodology was developed to apply best practices in research synthesis in clinical medicine and environmental health to the evidence streams common in environmental health science (i.e., experimental toxicological studies and observational human studies) in order to reach an overall conclusion about the strength of evidence (Woodruff et al. 2011a).
Experimental toxicological studies show that exposing bronchial epithelial cells to nitrogen dioxide causes oxidative stress [ 76], production of pro-inflammatory molecules [ 77, 78], suppression of the innate response [ 79, 80], impaired macrophage activation [ 81], and altered function of surfactant proteins which are critical in phagocytosis and inflammation processes [ 76].
