Exact(2)
At the same time, participants agreed that development of strategies to detect and protect against potentially hazardous chemicals in the environment will benefit from information sharing with international colleagues who possess extensive toxicological experience.
In this case, past toxicological experience may support the threshold hypothesis, whereas other lines of evidence (such as the proposed molecular mechanisms by which EDCs could disrupt development and generate irreversible effects on endocrine-sensitive organs) support the no-threshold hypothesis.
Similar(58)
The research panel included physicians experienced in making occupational health and toxicological assessments, clinical toxicologists, and an epidemiologist.
At the time, I had 10 years experience as a research associate doing both toxicological and wildlife research at the University of Guelph and Ontario Veterinary College," she says.
The nomenclatures produced by the toxicological pathologists represent the distillation of many years of pathology experience and so offer a robust route for recognising common lesions.
By identifying a committee member as having environmental public health expertise, we mean that this individual has experience in evaluation of or response to the direct toxicological effects of chemical and physical agents on human health or indirect effects such as psychosocial stresses, highway safety, and drug and alcohol abuse.
A corollary of this is that toxicological assessments of TDCs should consider the natural range of temperatures that a species experiences, or is predicted to experience in future.
The Working Group on Toxicant-induced Loss of Tolerance has formulated a series of research questions to test this hypothesis: Do some individuals experience sensitivity to chemicals at levels of exposure unexplained by classical toxicological thresholds and dose-response relationships, and outside normally expected variation in the population?
If basic research is to increase our ability to predict the consequences of exposure to environmental chemicals, we must embrace nonreductionist thinking and design experimental models that emulate human experience, including but not limited to the interactions between infections and toxicological exposures.
Toxicological sciences: an official journal of the Society of Toxicology 71, 276 281 (2003).
Since disaster situations provide large experience in syndrome medicine (such as crush and blast injuries, inhalation burns, and toxicological threats), the state of the art in critical care response has been described elsewhere [ 4].
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