Sentence examples for toxicological dose from inspiring English sources

A careful evaluation of the toxicology and pharmacology literatures suggests that the biphasic dose response that characterizes hormesis may be much more widespread than is commonly recognized, and may come to rival our currently favored ideas about toxicological dose responses confined to the linear and threshold representations used in risk assessment.

In contrast, compounds reported in silicone PSDs represent only the vapor phase, which may encompass 34 86% of the toxicological dose of PAHs in industrial exposures.

In this, it may be especially scrutinized that the incidence of alveolar and bronchiolar adenoma or carcinoma were used as critical responses for obtaining the toxicological dose descriptors [ 5].

Benchmark doses and toxicological dose descriptors were obtained by searching with the key words 'ethyl carbamate' or 'urethan e)' and 'margin of exposure'MOEMOE'benchmarkark dose'BMDBMD'BMDLMDL'BMDL10L10' or 'T25'.

The literature search revealed two international risk assessments by the JECFA [ 5] and EFSA [ 4], as well as articles by O'Brien et al. [ 54] and Schlatter et al. [ 55] that contained data on toxicological dose descriptors for EC.

Thus, we elaborated that FJHQT extract has higher safety index in its antinociceptive and anti-inflammatory activities because the content of tetrandrine in the used dosage of FJHQT extract for the antinociceptive and anti-inflammatory tests is about 25 – 250 μg/g body weight (thousandth of chronic toxicological dose).

However, in order to be able to detect adverse effects utilizing classical toxicological endpoints, dose selection has historically involved the use of high dose levels and appropriate dose level spacing to obtain the LOAEL or no-observed-adverse-effect level thresholds.

Thus, the approach described in this paper is a synthesis of the classical concept of toxicology of air pollutants (critical concentrations) and the more toxicological relevant dose concept.

In addition, an acute extended single-dose toxicological study was performed in mice (n = 5) at the dose of 5 mg/kg, a dose being more that 2500-fold higher than the expected human dose for F-radiolabled NST-732 for clinical PET studies.

Data from the zebrafish embryo toxicity test had indicated that combined exposure of the two chemicals increased the toxicological effects with dose dependence.

It notes that with respect to children the toxicological maxim "'the dose makes the poison' does not always adequately describe the exposure health outcome relationship".