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However, only few investigations are focusing on the biomedical or toxicological relationship associated with this parameter alone.
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Interactions between biological control agents (insect predators, parasitoids, and pathogens) and GM crops exceed simple toxicological relationships, a priority for assessing risk of GM crops to non-target species.
We first sought to observe if the CTD contained toxicological relationships between environmental chemicals and genes with variants identified in association studies (Fig. 2).
Next, we search for evidence of toxicological relationships between these genetic and environmental factors that may have an etiological role in the disease.
Field studies are poorly suited for determining toxicological cause effect relationships.
Clinical pathology evaluations therefore assist in establishing toxicological dose response relationships in the preclinical safety assessment of a test article.
Moreover, the study of the relationship between toxicological effects and physico-chemical characteristics of particles suggests that surface area does not play a primary role in the cytotoxicity.
Different designs can be used to analyze the relationships between respiratory mortality and long term exposure to atmospheric pollution: epidemiological studies (cohort, prevalence study) demonstrate the reality of the relationship and toxicological studies explain it.
It is relevant to satisfying the chemical safety assessment requirements of the REACH legislation as it supports access to experimental data, (Quantitative) Structure-Activity Relationship models, and toxicological information through an integrating platform that adheres to regulatory requirements and OECD validation principles.
The prediction of toxicological activity using quantitative structure activity relationship (QSAR) methods was among the first applications of computational approaches in toxicology.
Statistical analysis can be used to evaluate the complex eco-toxicological processes by showing the relationship and interdependency among the variables and their relative weights.
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